4
CLEVELAND CLINIC JOURNAL OF MEDICINE VOLUME 79 • NUMBER 1 JANUARY 2012
TABLE OF CONTENTS
FROM THE EDITOR ............................................................................
Bugs, pundits, evolution, and the New Year 10
Pathogens continue to evolve, in uenced by human behavior
but untouched by partisan dialogue and undaunted by doubting
politicians.
B.F. MANDELL
THE CLINICAL PICTURE ......................................................................
Cytomegalovirus colitis 12
Cytomegalovirus colitis is common in patients on immuno-
suppressive therapy for in ammatory bowel disease.
J.G. HASHASH, M. REFAAT, A. ABDULBAKI, E.G. AOUN, AND L. BAIDOO
THE CLINICAL PICTURE ......................................................................
Diffuse reticulonodular infi ltrates 16
A 69-year-old woman has fever of unknown origin
and dyspnea. Her past provides a clue to the diagnosis.
M.G.S. VELEZ AND V.J.M. VELEZ JR.
1-MINUTE CONSULT ..........................................................................
Should target natriuretic peptide levels 22
be used for outpatient management
of chronic heart failure?
Results of trials have been inconclusive, and there is
not enough evidence to recommend doing it routinely.
A. IBRAHIM, M. BAIBARS, M.C. ALRAIES, AND G.H. OLIVEIRA
MEDICAL GRAND ROUNDS .................................................................
Updates in the medical management 28
of Parkinson disease
The features of Parkinson disease, its treatment options,
and its complications in moderate to advanced disease.
H.H. FERNANDEZ
INTERPRETING KEY TRIALS ................................................................
Is niacin ineffective? 38
Or did AIM-HIGH miss its target?
A trial has thrown the use of niacin as a lipid-modifying
therapy into question. But the results can be interpreted
in several ways.
S.J. NICHOLLS
CONTINUED ON PAGE 9
JANUARY 2012
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■ Overcoming disparities
via better communication
■ Protease inhibitors:
Silver bullets for hepatitis C
■ Deep brain stimulation:
What can we expect fr
om it?
■ Chronic kidney disease
in African Americans:
Challenges and opportunities
■ Recognizing the risk
of PTSD and suicide
in veterans
■ Acute community-acquired
bacterial meningitis in adults
■ C-reactive protein:
Marker or mediator
of cor
onary artery disease?
UPCOMING
FEATURES
CONTINUED FROM PAGE 4
JANUARY 2012
CLEVELAND CLINIC JOURNAL OF MEDICINE VOLUME 79 • NUMBER 1 JANUARY 2012
9
SERIES INTRODUCTION .....................................................................
Addressing disparities in health care 44
We launch a series we hope will provide practical tools
to address the disparities in our health care system.
C.S. MODLIN
ADDRESSING DISPARITIES IN HEALTH CARE ........................................
Overcoming barriers to hypertension control 46
in African Americans
We review the evidence on practice-based approaches
to improving blood pressure control, focusing on studies
in African Americans.
T. ODEDOSU, A. SCHOENTHALER, D.L. VIEIRA, C. AGYEMANG, AND G. OGEDEGBE
REVIEW ...........................................................................................
Skin and soft-tissue infections: 57
Classifying and treating a spectrum
Early recognition, close follow-up, and familiarity
with local antibiotic susceptibility are critical to
successful treatment.
S. RAJAN
REVIEW ...........................................................................................
Managing community-acquired pneumonia 67
during fl u season
In uenza can present as community-acquired pneumonia
and should be included in the differential diagnosis.
S. HAESSLER AND J.J. SCHIMMEL
DEPARTMENTS .................................................................................
CME Calendar 8
Correction 78
An error appeared in Sabella C. Measles: Not just a childhood
rash. Cleve Clin J Med 2010; 77:207–213.
Directions for taking CME tests online 79
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articles in this issue (those that carry the CME logo), then go to
www.ccjm.org to take the test for the article or articles you select.
It should take up to 1 hour to complete the activity for each
article.
Release date: January 1, 2012
Expiration date: December 31, 2012
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