Gender-Affirming Care and Young People
HHS Office of Population Affairs
Web: opa.hhs.gov | Email: opa@hhs.gov | Twitter: @HHSPopAffairs
YouTube: HHSOfficeofPopulationAffairs | LinkedIn: HHS Office of Population Affairs
Gender-affirming care is a supportive form of healthcare. It consists of
an array of services that may include medical, surgical, mental health,
and non-medical services for transgender and nonbinary people.
For transgender and nonbinary children and adolescents, early gender-
affirming care is crucial to overall health and well-being as it allows the
child or adolescent to focus on social transitions and can increase their
confidence while navigating the healthcare system.
Research demonstrates that gender-affirming care improves the mental
health and overall well-being of gender diverse children and
adolescents.
1
Because gender-affirming care encompasses many facets
of healthcare needs and support, it has been shown to increase positive
outcomes for transgender and nonbinary children and adolescents.
Gender-affirming care is patient-centered and treats individuals
holistically, aligning their outward, physical traits with their gender
identity.
Gender diverse adolescents face significant health disparities compared
to their cisgender peers. Transgender and gender nonbinary adolescents
are at increased risk for mental health issues, substance use, and
suicide.
2,3
The Trevor Project’s 2021 National Survey on LGBTQ Youth
Mental Health found that 52 percent of LGBTQ youth seriously
considered attempting suicide in the past year.
4
A safe and affirming healthcare environment is critical in fostering better
outcomes for transgender, nonbinary, and other gender expansive
children and adolescents. Medical and psychosocial gender affirming
healthcare practices have been demonstrated to yield lower rates of
adverse mental health outcomes, build self-esteem, and improve overall
quality of life for transgender and gender diverse youth.
5,6
Familial and peer support is also crucial in fostering
similarly positive outcomes for these populations. The presence of affirming support networks is critical for
facilitating and arranging gender affirming care for children and adolescents. Lack of such support can result in
rejection, depression and suicide, homelessness, and other negative outcomes.
7,8,9
What is gender-affirming care?
Why does it matter?
Common Terms
Cisgender: Describes a person
whose gender identity aligns with
their sex assigned at birth
Gender diverse or expansive: An
umbrella term for a person with a
gender identity and/or expression
broader than the male or female
binary. Gender minority is also used
interchangeably with this term
Gender dysphoria: Clinically
significant distress that a person may
feel when sex or gender assigned at
birth is not the same as their identity
Gender identity: One’s internal
sense of self as man, woman, both
or neither
Nonbinary: Describes a person who
does not identify with the man or
woman gender binary
Transgender: Describes a person
whose gender identity and or
expression is different from their sex
assigned at birth, and societal and
cultural expectations around sex
HHS uses LGBTQI+ (lesbian, gay,
bisexual, transgender,
queer/questioning, or intersex) to reflect
the diversity of this community. More
specific terms are used in alignment with
research and information sources.
However, people who are part of this
community may use various other
terms to define their identity.
Additional Information
Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical
Practice Guideline
Ensuring Comprehensive Care and Support for Transgender and Gender-Diverse Children and
Adolescents | American Academy of Pediatrics
Standards of Care (SOC) for the Health of Transsexual, Transgender, and Gender Nonconforming People
| World Professional Association for Transgender Health
Gender-Affirming Care and Young People
HHS Office of Population Affairs
Web: opa.hhs.gov | Email: opa@hhs.gov | Twitter: @HHSPopAffairs
YouTube: HHSOfficeofPopulationAffairs | LinkedIn: HHS Office of Population Affairs
Affirming care What is it? When is it used? Reversible or not
Social Affirmation
Adopting gender-affirming hairstyles,
clothing, name, gender pronouns, and
restrooms and other facilities
At any age or stage
Reversible
Puberty Blockers
Using certain types of hormones to
pause pubertal development
During puberty
Reversible
Hormone Therapy
Testosterone hormones for those who
were assigned female at birth
Estrogen hormones for those who were
assigned male at birth
Early adolescence
onward
Partially reversible
Gender-Affirming
Surgeries
“Top” surgery to create male-typical
chest shape or enhance breasts
“Bottom” surgery surgery on genitals
or reproductive organs
Facial feminization or other procedures
Typically used in
adulthood or case-
by-case in
adolescence
Not reversible
Resources
Discrimination on the Basis of Sex | HHS Office of Civil Rights
Lesbian, Gay, Bisexual, and Transgender Health | Healthy People 2030
Lesbian, Gay, Bisexual, and Transgender Health: Health Services | Centers for Disease Control and Prevention
National Institutes of Health Sexual & Gender Minority Research Office
Family Support: Resources for Families of Transgender & Gender Diverse Children | Movement Advancement Project
Five Things to Know About Gender-Affirming Health Care | ACLU
Gender-Affirming Care is Trauma-Informed Care | The National Child Traumatic Stress Network
Gender-Affirming Care Saves Lives | Columbia University
Gender Identity | The Trevor Project
Genderspectrum.org
Glossary of Terms | Human Rights Campaign
Health Care for Transgender and Gender Diverse Individuals | ACOG
Transgender and Gender Diverse Children and Adolescents | Endocrine Society
1
Green, A. E., DeChants, J. P., Price, M. N., and Davis, C. K. (2021). Association of Gender-Affirming Hormone Therapy With Depression, Thoughts of
Suicide, and Attempted Suicide Among Transgender and Nonbinary Youth. Journal of Adolescent Health, 70(4).
https://doi.org/https://doi.org/10.1016/j.jadohealth.2021.10.036
2
Rimes, K., Goodship N., Ussher, G., Baker, D. and West, E. (2019). Non-binary and binary transgender youth: Comparison of mental health, self-
harm, suicidality, substance use and victimization experiences. International Journal of Transgenderism, 20 (2-3); 230-240.
3
Price-Feeney, M., Green, A. E., & Dorison, S. (2020). Understanding the mental health of transgender and nonbinary youth. Journal of Adolescent
Health, 66(6), 684690. https://doi.org/10.1016/j.jadohealth.2019.11.314
4
Trevor Project. (2021). National Survey on LGBTQ Youth Mental Health 2021. Trevor Project. https://www.thetrevorproject.org/survey-2021/
5
Wagner J, Sackett-Taylor AC, Hodax JK, Forcier M, Rafferty J. (2019). Psychosocial Overview of Gender-Affirmative Care. Journal of pediatric and
adolescent gynecology, (6):567-573. doi: 10.1016/j.jpag.2019.05.004. Epub 2019 May 17. PMID: 31103711.
6
Hughto JMW, Gunn HA, Rood BA, Pantalone DW. (2020). Social and Medical Gender Affirmation Experiences Are Inversely Associated with Mental
Health Problems in a U.S. Non-Probability Sample of Transgender Adults. Archives of sexual behavior, 49(7):2635-2647. doi: 10.1007/s10508-020-
01655-5. Epub 2020 Mar 25. PMID: 32215775; PMCID: PMC7494544.
7
Brown, C., Porta, C. M., Eisenberg, M. E., McMorris, B. J., & Sieving, R. E. (2020). Family relationships and the health and well-being of transgender
and gender-diverse youth: A critical review. LGBT Health, 7, 407-419. https://doi.org/10.1089/lgbt.2019.0200
8
Seibel BL, de Brito Silva B, Fontanari AMV, Catelan RF, Bercht AM, Stucky JL, DeSousa DA, Cerqueira-Santos E, Nardi HC, Koller SH, Costa AB.
(2018). The Impact of the Parental Support on Risk Factors in the Process of Gender Affirmation of Transgender and Gender Diverse People. Front
Psychol, 27;9:399. doi: 10.3389/fpsyg.2018.00399. Erratum in: Front Psychol. 2018 Oct 12;9:1969. PMID: 29651262; PMCID: PMC5885980.
9
Sievert ED, Schweizer K, Barkmann C, Fahrenkrug S, Becker-Hebly I. (2021). Not social transition status, but peer relations and family functioning
predict psychological functioning in a German clinical sample of children with Gender Dysphoria. Clin Child Psychol Psychiatry, 26(1):79-95. doi:
10.1177/1359104520964530. Epub 2020 Oct 20. PMID: 33081539.